Okay, let me ask that we use restraint in this thread. No politics, nothing about fellow members here, etc... Let's keep this light in nature.
With that in mind, Vista's been driving me nuts from the day I installed it. Let's see:
Vista couldn't even recognize my card/driver (not even the vendor? I had to dig up the receipt...), and the hardware vendor's site informed me my sound card is no longer supported! I figured out a workaround, 3 hours later... Fortunately, by tweaking a specific sound driver, on a number of different levels, that was never intended for my sound card, I get the desired result: Quality Audio Output!
Here's how you check to see if your soundcard is supported:
http://winqual.microsoft.com/HCL/ProductList.aspx?m=v&g=d&cid=110&f=86p
Next up, Access (XP) quit working!
The fix is easy enough, if you're running Office XP in Windows Vista, you're going to want to hook yourself up with Office SP3:
http://www.microsoft.com/downloads/details.aspx?FamilyID=85AF7BFD-6F69-4289-8BD1-EB966BCDFB5E
I'm getting other quirks with it, too. Lots of irritating pop-ups about programs not working, nothing is allowed to run without clicking through dialogs (i.e., open a zip file from the web) and for some reason it likes to kill my Internet connection following Windows Updates, which requires a reboot. Cripes...