Congratulations! You're the first person I have personally seen that wants more than the new limit of 16,384 columns. Not sure how you woulda survived with the mere 256 columns we lived with up until 2007.
So no - ya cain't get there from here.
OK - Annie, let's just do a comprehension check by shrinking the scale...
Do you want to take what's shown in B1:B5 and change it to what's shown in A7:E7?
Or vice-versa?
....
Because you cannot to the former for more than 16384 rows. However, yes, you could to the latter with no problem.
Greg, I think she may have explained herself incorrectly. She is trying to transpose the contents of a single row into a column. Take a look at her screenshots.