Maybe (change Sheet1 to suit. Why do you state "my specified sheet" then not state it?????) ...
Code:
Sub CleanTrim()
Dim myArea As Range
For Each myArea In Sheets("Sheet1").Rows(1).Areas
myArea.Value = Evaluate("IF(ROW(" & myArea.Address & "),CLEAN(TRIM(" & myArea.Address & ")))")
Next myArea
End Sub
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