Protect a particular column in Excel

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Use Data, What-If Analysis, Goal Seek to find the correct input cell value to reach a desired result
If you have not made any changes to any cells, then by default all cells are already checked marked to be locked. Select a cell and right click...format cells. Go to the protection tab and you will see a box to check for locked. If you uncheck that box then when you apply protection that cell/row/column will be unprotected.
 
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