Improve performance with large file

[Soraka]

I have a big amount of functions, checkboxes and vba running both on loop and activation from myself.
If I calculate, I experience a large slow down.
I have a 7950x3d, fast and large NVME, 4090 (but doubt that matters) and 64GB fast ram (30CL).

Is there a way to drastically decrease the slow downs I experience while calculating?

I saw this answer (from another post, a year ago on Reddit), that might give suggestions to you, who may know what that means (in quotes).
I don't understand any of what is below, but I would like to implement these, if possible.
Of course, if you have any other suggestions, please tell me.

Connecting to the data in a separate CSV with Power Query and loading into the data model(Power Pivot) then doing the calculations with DAX then building pivots from the data model should make an enormous difference.

 

[kevin9999]

Is it possible to share your actual file (with sensitive data removed/disguised)? Sometimes there are faster methods using VBA than normal calculations; loops can sometimes be avoided, but without knowing your file structure etc it's impossible to give any definitive advice.