You see that Missing Library Reference? If you have that, get rid of it, then click File->Save.
Otherwise, Colo's HTML Maker is an Excel Add-In; it doesn't interfere with anything Hyperion Essbase that I know of, having used both, together, to fairly a significant extent.
If you really want to get rid of it, uncheck the Add-in and delete it, it's an .XLA file.
The one other thing I might check is any Adobe add-ins you may have, these have caused odd problems, historically.
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