It appears that you've got a fairly significant project. It's hard to see how I can help here, since this site is dedicated more to answering questions about pieces of a puzzle, not designing the puzzle. You may want to get a consultant.
Nevertheless, I can suggest how to do part of it. Let's say your Guide sheet looks like this:
| A | B | C | D | E | F | G | H | I | J | K | L | M | N |
---|
Questions | Response 1 | Response 2 | Response 3 | Response 4 | Select | | | | | | | | | |
How many? | A lot | None | | | | | | | | | | | | |
When? | Never | 1st of June | | | | | | | | | | | | |
What time? | Noon | | | | | | | | | | | | | |
Pet's name? | Spot | Fido | Jinx | | | | | | | | | | | |
Favorite State? | Maine | Florida | Iowa | | | | | | | | | | | |
Zodiac sign? | Aries | Cancer | Leo | Pisces | | | | | | | | | | |
Age? | | | | | | | | | | | | | | |
Height? | 5" | 6" | | | | | | | | | | | | |
Month? | June | December | | | | | | | | | | | | |
Color? | Red | Blue | Green | | | | | | | | | | | |
Class? | Algebra | English | History | | | | | | | | | | | |
<colgroup><col style="width: 25pxpx"><col><col><col><col><col><col><col><col><col><col><col><col><col><col></colgroup><thead>
</thead><tbody>
[TD="align: center"]1[/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: center"]2[/TD]
[TD="align: right"]1[/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"]2[/TD]
[TD="align: center"]3[/TD]
[TD="align: right"]2[/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"]4[/TD]
[TD="align: center"]4[/TD]
[TD="align: right"]3[/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"]6[/TD]
[TD="align: center"]5[/TD]
[TD="align: right"]4[/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"]7[/TD]
[TD="align: center"]6[/TD]
[TD="align: right"]5[/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"]9[/TD]
[TD="align: center"]7[/TD]
[TD="align: right"]6[/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"]10[/TD]
[TD="align: center"]8[/TD]
[TD="align: right"]7[/TD]
[TD="align: right"]10[/TD]
[TD="align: right"]20[/TD]
[TD="align: right"][/TD]
[TD="align: right"]30[/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"]11[/TD]
[TD="align: center"]9[/TD]
[TD="align: right"]8[/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"]3[/TD]
[TD="align: center"]10[/TD]
[TD="align: right"]9[/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"]5[/TD]
[TD="align: center"]11[/TD]
[TD="align: right"]10[/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: center"]12[/TD]
[TD="align: right"]11[/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
[TD="align: right"][/TD]
</tbody>
Your questions are in column B, then answers in C:F. In column N is the list of questions you want to put on the MyQs sheet. You'd select them according to your initial questions. These could be asked from a UserForm, kicked off by a Worksheet_Open event perhaps. That's another piece.
Now right click on the sheet tab on the bottom and select View Code. From the menu, click Insert > Module. Then paste this code:
Change the sheet names in red to match your sheet, and the sheets must exist. Now close the VBA editor, and in the Excel window press Alt-F8, select the MakeQs macro and click Run. The questions selected from the Guide sheet will be copied to the MyQs sheet, and a Data Validation (without spaces!) will be copied to the cell next to the question.
Hopefully this gives you some direction.